The Jags travel to Starkville to face the struggling Mississippi State Bulldogs Wednesday night at Dudy Noble Field.
Southern (7-18, 4-7) has lost five in a row and is currently 3.5 games back of Grambling State in the SWAC West division.
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The Jaguar offense is led by Franky Montesino (.352), Zavier Moore (.343) and Tyler LaPorte (.330).
The Bulldogs (14-15, 2-7) lost two-out-of-three to LSU over the weekend and have lost four of their last five contests.
Jake Mangum leads the Bulldog hitting attack with a .328 batting average. He has nine doubles, two triples, and seven RBI.
First pitch between the Jaguars and Bulldogs is set for 6:30 p.m. at Dudy Noble Field in Starkville.
After Wednesday's game, the Jags return home to host Arkansas-Pine Bluff at Lee-Hines Field beginning Friday.
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